研究與開發(fā)
- Lin H, An Y, Tang H and Wang Y, "Alterations of Bile Acids and Gut Microbiota in Obesity Induced by High Fat Diet in Rat Model", J Agric .Food Chem. 67: 3624-3632, 2019.
- Nicholson JK, Connelly J, Lindon JC, et al., "Metabonomics: a platform for studying drug toxicity and gene function", Nature Reviews Drug Discovery, 1: 153-161, 2002.
- Nicholson JK, Holmes E, Wilson ID, "Gut microorganisms, mammalian metabolism and personalized health care", Nature Reviews Microbiology, 3: 431-438, 2005.
- Clayton TA, Lindon JC, Cloarec O, et al., "Pharmaco-metabonomic phenotyping and personalized drug treatment", Nature, 440: 1073-1077, 2006.
- Martin F-PJ, Wang Y, Sprenger N, et al., "Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model", Molecular Systems Biology, 4: 1-17, 2008.
- Claus SP, Tsang TM, Wang Y, et al., "Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes", Molecular Systems Biology, 4: 1744-4292, 2008.
- Martin F-PJ, Wang Y, Sprenger N, et al., "Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model", Molecular Systems Biology, 4: 1-15, 2008.
- Li M, Wang B, Zhang M, et al., "Symbiotic gut microbes modulate human metabolic phenotypes", Proc Natl Acad Sci USA, 105: 2117-2122, 2008.
- Holmes E, Loo RL, Stamler J, et al., " Human metabolic phenotype diversity and its association with diet and blood pressure", Nature, 453: 396-400, 2009.
- Clayton TA, Baker D, Lindon JC, et al. "Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism", Proc Natl Acad Sci USA, 106: 14728-14733,2009.
- Fonville JM, Maher AD, Coen M, et al., "Evaluation of full-resolution J-resolved 1H NMR projections of biofluids for metabonomics information retrieval and biomarker identification" , Anal Chem, 82: 1811-1821,2010.
- Heinzmann SS, Brown IJ, Chan Q, et al., "Metabolic profiling strategy for discovery of nutritional biomarkers: proline betaine as a marker of citrus consumption", Am J Clin Nutr, 92: 436-443,2010.
- Swann JR, Want EJ, Geier FM, et al., “Systemic gut microbial modulation of bile acid metabolism in host tissue compartments”, Proc Natl Acad Sci USA, 108: 4523-4530, 2011.
- Sands CJ, Coen M, Ebbels TM, et al., “Data-driven approach for metabolite relationship recovery in biological 1H NMR data sets using iterative statistical total correlation spectroscopy”, Anal Chem, 83: 2075-2082，2011.
- Z.D. Xu, K.Harvey, T.Pavlina, et al.,"An Improved Method for Determining Medium- and Long-Chain FAMEs Using Gas Chromatography", Lipids, 45: 199-208, 2010.
- O. Beckonert, M. Coen, H.C. Keun, et al., "High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues", nature protocols, 5 (6): 1019-1032, 2010.
- J.F. Wu, Y.P. An, J.W. Yao, et al., "An optimised sample preparation method for NMR-based faecal metabonomic analysis", Analyst, 135:1023-1030, 2010.
- C.N. Xiao, F.H. Hao, X.R. Qin, et al., "An optimized buffer system for NMR-based urinary metabonomics with effective pH control, chemical shift consistency and dilution minimization", Analyst, 134: 916-925, 2009.
- L.M. Jiang, J. Huang, Y.L. Wang, et al., "Eliminating the dication-induced intersample chemical-shift variations for NMR-based biofluid metabonomic analysis", Analyst, 137: 4209-4219, 2012.
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